NHE9 induces chemoradiotherapy resistance in esophageal squamous cell carcinoma by upregulating the Src/Akt/β-catenin pathway and Bcl-2 expression

Recently, we found that NHE9 mRNA was upregulated in chemoradiotherapy (CRT)-resistant esophageal squamous cell carcinoma (ESCC); however, the underlying mechanisms were unclear. Here, we aimed to clarify the functional contribution of NHE9 to CRT resistance, understand the molecular basis of NHE9-d...

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Udgivet i:Oncotarget
Main Authors: Chen, Junying, Yang, Hong, Wen, Jing, Luo, Kongjia, Liu, Qianwen, Huang, Yijie, Zheng, Yuzhen, Tan, Zihui, Qingyuan Huang, Qinyuan, Fu, Jianhua
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494947/
https://ncbi.nlm.nih.gov/pubmed/25915159
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