Molecular stratification of metastatic melanoma using gene expression profiling : Prediction of survival outcome and benefit from molecular targeted therapy

Melanoma is currently divided on a genetic level according to mutational status. However, this classification does not optimally predict prognosis. In prior studies, we have defined gene expression phenotypes (high-immune, pigmentation, proliferative and normal-like), which are predictive of surviva...

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Publicat a:Oncotarget
Autors principals: Cirenajwis, Helena, Ekedahl, Henrik, Lauss, Martin, Harbst, Katja, Carneiro, Ana, Enoksson, Jens, Rosengren, Frida, Werner-Hartman, Linda, Törngren, Therese, Kvist, Anders, Fredlund, Erik, Bendahl, Pär-Ola, Jirström, Karin, Lundgren, Lotta, Howlin, Jillian, Borg, Åke, Gruvberger-Saal, Sofia K., Saal, Lao H., Nielsen, Kari, Ringnér, Markus, Tsao, Hensin, Olsson, Håkan, Ingvar, Christian, Staaf, Johan, Jönsson, Göran
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494939/
https://ncbi.nlm.nih.gov/pubmed/25909218
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