Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer

Non-small cell lung cancer (NSCLC) remains the most common cause of cancer death worldwide due its resistance to chemotherapy and aggressive tumor growth. Polo-like kinase 1 (PLK1) is a serine-threonine protein kinase which is overexpressed in cancer cells, and plays a major role in regulating tumor...

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Veröffentlicht in:Oncotarget
Hauptverfasser: McCarroll, Joshua A., Dwarte, Tanya, Baigude, Huricha, Dang, Jason, Yang, Lu, Erlich, Rafael B., Kimpton, Kathleen, Teo, Joann, Sagnella, Sharon M., Akerfeldt, Mia C., Liu, Jie, Phillips, Phoebe A., Rana, Tariq M., Kavallaris, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494920/
https://ncbi.nlm.nih.gov/pubmed/25557168
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