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Modeling Contaminants in AP-MS/MS Experiments

Identification of protein–protein interactions (PPI) by affinity purification (AP) coupled with tandem mass spectrometry (AP-MS/MS) produces large data sets with high rates of false positives. This is in part because of contamination at the AP level (due to gel contamination, nonspecific binding to...

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Detalles Bibliográficos
Publicado en:J Proteome Res
Autores principales: Lavallée-Adam, Mathieu, Cloutier, Philippe, Coulombe, Benoit, Blanchette, Mathieu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494835/
https://ncbi.nlm.nih.gov/pubmed/21117706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100795z
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