Extracellular signal-regulated kinase activation in the amygdala mediates elevated plus maze behavior during opioid withdrawal

This study examined whether activation of extracellular signal-regulated kinase (ERK) contributes to the increased open-arm time observed in the elevated plus maze (EPM) during opioid withdrawal. We applied SL327, a selective ERK kinase (MEK) inhibitor, to specific limbic areas and examined the effe...

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Veröffentlicht in:Behav Pharmacol
Hauptverfasser: Hofford, Rebecca S., Hodgson, Stephen R., Roberts, Kris W., Bryant, Camron D., Evans, Christopher J., Eitan, Shoshana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494789/
https://ncbi.nlm.nih.gov/pubmed/19738463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32832ec57e
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