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High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor

Accurate optical reporting of electrical activity in genetically defined neuronal populations is a long-standing goal in neuroscience. Here we describe Accelerated Sensor of Action Potentials 1 (ASAP1), a novel voltage sensor design in which a circularly permuted green fluorescent protein is inserte...

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Bibliografiske detaljer
Udgivet i:Nat Neurosci
Main Authors: St-Pierre, François, Marshall, Jesse D, Yang, Ying, Gong, Yiyang, Schnitzer, Mark J, Lin, Michael Z
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494739/
https://ncbi.nlm.nih.gov/pubmed/24755780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3709
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