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Immunosuppressive nano-therapeutic micelles downregulate endothelial cell inflammation and immunogenicity

In this study, we developed a stable, nontoxic novel micelle nanoparticle to attenuate responses of endothelial cell (EC) inflammation when subjected to oxidative stress, such as observed in organ transplantation. Targeted Rapamycin Micelles (TRaM) were synthesized using PEG-PE-amine and N-palmitoyl...

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Detalhes bibliográficos
Publicado no:RSC Adv
Main Authors: Nadig, Satish N., Dixit, Suraj K., Levey, Natalie, Esckilsen, Scott, Miller, Kayla, Dennis, William, Atkinson, Carl, Broome, Ann-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494678/
https://ncbi.nlm.nih.gov/pubmed/26167278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5RA04057D
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