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Immunosuppressive nano-therapeutic micelles downregulate endothelial cell inflammation and immunogenicity
In this study, we developed a stable, nontoxic novel micelle nanoparticle to attenuate responses of endothelial cell (EC) inflammation when subjected to oxidative stress, such as observed in organ transplantation. Targeted Rapamycin Micelles (TRaM) were synthesized using PEG-PE-amine and N-palmitoyl...
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Publicado no: | RSC Adv |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494678/ https://ncbi.nlm.nih.gov/pubmed/26167278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5RA04057D |
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