Development of a fluorescent reporter system to delineate cancer stem cells in triple-negative breast cancer

Advanced cancers display cellular heterogeneity driven by self-renewing, tumorigenic cancer stem cells (CSCs). The use of cell lines to model CSCs is challenging due to the difficulty of identifying and isolating cell populations that possess differences in self-renewal and tumor initiation. To over...

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Pubblicato in:Stem Cells
Autori principali: Thiagarajan, Praveena S., Hitomi, Masahiro, Hale, James S., Alvarado, Alvaro G., Otvos, Balint, Sinyuk, Maksim, Stoltz, Kevin, Wiechert, Andrew, Mulkearns-Hubert, Erin, Jarrar, Awad, Zheng, Qiao, Thomas, Dustin, Egelhoff, Thomas, Rich, Jeremy N., Liu, Huiping, Lathia, Justin D., Reizes, Ofer
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494654/
https://ncbi.nlm.nih.gov/pubmed/25827713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2021
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