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Animal models of ischemic stroke and their application in clinical research

This review outlines the most frequently used rodent stroke models and discusses their strengths and shortcomings. Mimicking all aspects of human stroke in one animal model is not feasible because ischemic stroke in humans is a heterogeneous disorder with a complex pathophysiology. The transient or...

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Publicado en:Drug Des Devel Ther
Main Authors: Fluri, Felix, Schuhmann, Michael K, Kleinschnitz, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494187/
https://ncbi.nlm.nih.gov/pubmed/26170628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S56071
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