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Native Liquid Extraction Surface Analysis Mass Spectrometry: Analysis of Noncovalent Protein Complexes Directly from Dried Substrates

Liquid extraction surface analysis (LESA) mass spectrometry is a promising tool for the analysis of intact proteins from biological substrates. Here, we demonstrate native LESA mass spectrometry of noncovalent protein complexes of myoglobin and hemoglobin from a range of surfaces. Holomyoglobin, in...

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Détails bibliographiques
Publié dans:J Am Soc Mass Spectrom
Auteurs principaux: Martin, Nicholas J., Griffiths, Rian L., Edwards, Rebecca L., Cooper, Helen J.
Format: Artigo
Langue:Inglês
Publié: Springer US 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494149/
https://ncbi.nlm.nih.gov/pubmed/25990922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-015-1152-8
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