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G15 sensitizes epithelial breast cancer cells to doxorubicin by preventing epithelial-mesenchymal transition through inhibition of GPR30

Resistance to single or multiple chemotherapeutic drugs is a major obstacle in breast cancer therapy. Recent studies have suggested that GPR30 is implicated in mediating cancer cell proliferation. The aim of this study was to examine the anti-tumor effects of the GPR30 antagonist G15 in breast cance...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Liu, Yu, Du, Fei-Ya, Chen, Wei, Fu, Pei-Fen, Yao, Min-Ya, Zheng, Shu-Sen
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494148/
https://ncbi.nlm.nih.gov/pubmed/26175858
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