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Intraperitoneal delivery of a novel liposome-encapsulated paclitaxel redirects metabolic reprogramming and effectively inhibits cancer stem cells in Taxol(®)-resistant ovarian cancer

Taxol(®) remained as the mainstay therapeutic agent in the treatment of ovarian cancer, however recurrence rate is still high. Cancer stem cells (CSCs) represent a subset of cells in the bulk of tumors and play a central role in inducing drug resistance and recurrence. Furthermore, cancer metabolism...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Shen, Yao-An, Li, Wai-Hou, Chen, Po-Hung, He, Chun-Lin, Chang, Yen-Hou, Chuang, Chi-Mu
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494136/
https://ncbi.nlm.nih.gov/pubmed/26175846
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