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Left-handed Z-DNA and in vivo supercoil density in the Escherichia coli chromosome.

A system for studying Z-DNA formation in the Escherichia coli chromosome was developed. Prior investigations in recombinant plasmids showed that alternating (Pur-Pyr) sequences can adopt a left-handed Z-DNA conformation both in vitro and in vivo. We constructed mobile, transposon-based cassettes car...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lukomski, S, Wells, R D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC44941/
https://ncbi.nlm.nih.gov/pubmed/7937930
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