Genetic Variants, Prediagnostic Circulating Levels of Insulin-like Growth Factors, Insulin, and Glucose and the Risk of Colorectal Cancer: The Multiethnic Cohort Study

BACKGROUND: Increased exposure of colonic and rectal epithelial cells to the promitotic and antiapoptotic effects of insulin and insulin-like growth factors (IGF) is hypothesized to increase colorectal cancer risk. METHODS: In a case–control study nested within the Multiethnic Cohort, we attempted t...

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Udgivet i:Cancer Epidemiol Biomarkers Prev
Main Authors: Ollberding, Nicholas J., Cheng, Iona, Wilkens, Lynne R., Henderson, Brian E., Pollak, Michael N., Kolonel, Laurence N., Le Marchand, Loïc
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494075/
https://ncbi.nlm.nih.gov/pubmed/22354904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-1105
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