Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function

Pericentriolar material (PCM) mediates the microtubule (MT) nucleation and anchoring activity of centrosomes. A scaffold organized by Centrosomin (Cnn) serves to ensure proper PCM architecture and functional changes in centrosome activity with each cell cycle. Here, we investigate the mechanisms tha...

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Vydáno v:J Cell Biol
Hlavní autoři: Lerit, Dorothy A., Jordan, Holly A., Poulton, John S., Fagerstrom, Carey J., Galletta, Brian J., Peifer, Mark, Rusan, Nasser M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494003/
https://ncbi.nlm.nih.gov/pubmed/26150390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503117
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