An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma based on mRNA, microRNA and DNA Methylation Biomarkers

INTRODUCTION: Up to 30% Stage I lung cancer patients suffer recurrence within 5 years of curative surgery. We sought to improve existing protein-coding gene and microRNA expression prognostic classifiers by incorporating epigenetic biomarkers. METHODS: Genome-wide screening of DNA methylation and py...

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Veröffentlicht in:J Thorac Oncol
Hauptverfasser: Robles, Ana I., Arai, Eri, Mathé, Ewy A., Okayama, Hirokazu, Schetter, Aaron J., Brown, Derek, Petersen, David, Bowman, Elise D., Noro, Rintaro, Welsh, Judith A., Edelman, Daniel C., Stevenson, Holly S., Wang, Yonghong, Tsuchiya, Naoto, Kohno, Takashi, Skaug, Vidar, Mollerup, Steen, Haugen, Aage, Meltzer, Paul S., Yokota, Jun, Kanai, Yae, Harris, Curtis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493931/
https://ncbi.nlm.nih.gov/pubmed/26134223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000560
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