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Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles

Active segregation of E. coli low-copy number plasmid R1 involves formation of a bipolar spindle made of left-handed double-helical actin-like ParM filaments (1-6). ParR links the filaments with centromeric parC plasmid DNA, while facilitating the addition of subunits to ParM filaments (3,7-9). Grow...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Bharat, Tanmay A.M., Murshudov, Garib N., Sachse, Carsten, Löwe, Jan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493928/
https://ncbi.nlm.nih.gov/pubmed/25915019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14356
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