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Intracellular spermine prevents acid-induced uncoupling of Cx43 gap junction channels

Polyamines (PAs), such as spermine and spermidine, modulate the activity of numerous receptors and channels in the central nervous system (CNS) and are stored in glial cells; however, little attention has been paid to their role in the regulation of connexin (Cx)-based gap junction channels. We have...

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Detalhes bibliográficos
Publicado no:Neuroreport
Main Authors: Skatchkov, Serguei N., Bukauskas, Feliksas F., Benedikt, Jan, Inyushin, Mikhail, Kucheryavykh, Yuriy V.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493885/
https://ncbi.nlm.nih.gov/pubmed/26011388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000385
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