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Sequence-Specific Purification of DNA Oligomers in Hydrophobic Interaction Chromatography Using Peptide Nucleic Acid Amphiphiles: Extended Dynamic Range

We present improvements on a previously reported method (Vernille JP, Schneider JW. 2004. Biotechnol Prog 20(6):1776–1782) to purify DNA oligomers by attachment of peptide nucleic acid amphiphiles (PNAA) to particular sequences on the oligomers, followed by their separation from unbound oligomers us...

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Publicat a:Biotechnol Bioeng
Autors principals: Savard, Jeffrey M., Schneider, James W.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493883/
https://ncbi.nlm.nih.gov/pubmed/17089392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.21242
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