Panax Notoginseng flower saponins (PNFS) inhibit LPS-stimulated NO overproduction and iNOS gene overexpression via the suppression of TLR4-mediated MAPK/NF-kappa B signaling pathways in RAW264.7 macrophages

BACKGROUND: Panax Notoginseng flower saponins (PNFS) are the main active component of Panax notoginseng (Burk) F. H. Chen flower bud (PNF) and possess significant anti-inflammatory efficacy. This study aims to explore the mechanisms underlying PNFS’ antiflammatory action in RAW264.7 macrophages. MET...

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Detalhes bibliográficos
Publicado no:Chin Med
Main Authors: Peng, Xiao-Xu, Zhang, Shu-Hui, Wang, Xiao-Ling, Ye, Ting-Jie, Li, Hua, Yan, Xiao-Feng, Wei, Li, Wu, Zhong-Ping, Hu, Jing, Zou, Chun-Pu, Wang, You-Hua, Hu, Xu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493833/
https://ncbi.nlm.nih.gov/pubmed/26155304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13020-015-0045-x
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