CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so

BACKGROUND: With more than 600,000 deaths from malaria, mainly of children under five years old and caused by infection with Plasmodium falciparum, comes an urgent need for an effective anti-malaria vaccine. Limited details on the mechanisms of protective immunity are a barrier to vaccine developmen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Med
Prif Awduron: Zhou, Jingling, Feng, Gaoqian, Beeson, James, Hogarth, P. Mark, Rogerson, Stephen J., Yan, Yan, Jaworowski, Anthony
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493812/
https://ncbi.nlm.nih.gov/pubmed/26149666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0391-7
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