The genetic architecture of NAFLD among inbred strains of mice

To identify genetic and environmental factors contributing to the pathogenesis of non-alcoholic fatty liver disease, we examined liver steatosis and related clinical and molecular traits in more than 100 unique inbred mouse strains, which were fed a diet rich in fat and carbohydrates. A >30-fold...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hui, Simon T, Parks, Brian W, Org, Elin, Norheim, Frode, Che, Nam, Pan, Calvin, Castellani, Lawrence W, Charugundla, Sarada, Dirks, Darwin L, Psychogios, Nikolaos, Neuhaus, Isaac, Gerszten, Robert E, Kirchgessner, Todd, Gargalovic, Peter S, Lusis, Aldons J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Genes and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493743/
https://ncbi.nlm.nih.gov/pubmed/26067236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05607
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