Quantitative and qualitative analysis of the novel antitumor 1,3,4-oxadiazole derivative (GLB) and its metabolites using HPLC-UV and UPLC-QTOF-MS

Fructose-based 3-acetyl-2,3-dihydro-1,3,4-oxadiazole (GLB) is a novel antitumor agent and belongs to glycosylated spiro-heterocyclic oxadiazole scaffold derivative. This research first reported a simple, specific, sensitive and stable high performance liquid chromatography -ultraviolet detector (HPL...

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Pubblicato in:Sci Rep
Autori principali: Li, Pu, Wang, Xin, Li, Jian, Meng, Zhi-Yun, Li, Shu-Chun, Li, Zhong-Jun, Lu, Ying-Yuan, Ren, Hong, Lou, Ya-Qing, Lu, Chuang, Dou, Gui-Fang, Zhang, Guo-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493701/
https://ncbi.nlm.nih.gov/pubmed/26148672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11906
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