Active mechanistic target of rapamycin plays an ancillary rather than essential role in zebrafish CNS axon regeneration

The developmental decrease of the intrinsic regenerative ability of the mammalian central nervous system (CNS) is associated with reduced activity of mechanistic target of rapamycin (mTOR) in mature neurons such as retinal ganglion cells (RGCs). While mTOR activity is further decreased upon axonal i...

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Udgivet i:Front Cell Neurosci
Main Authors: Diekmann, Heike, Kalbhen, Pascal, Fischer, Dietmar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493654/
https://ncbi.nlm.nih.gov/pubmed/26217179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00251
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