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Fibroblastic Transformation of Corneal Keratocytes by Rac Inhibition is Modulated by Extracellular Matrix Structure and Stiffness

The goal of this study was to investigate how alterations in extracellular matrix (ECM) biophysical properties modulate corneal keratocyte phenotypes in response to specific wound healing cytokines and Rho GTPases. Rabbit corneal keratocytes were plated within standard collagen matrices (2.5 mg/mL)...

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Detalles Bibliográficos
Publicado en:J Funct Biomater
Main Authors: Petroll, W. Matthew, Lakshman, Neema
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493509/
https://ncbi.nlm.nih.gov/pubmed/25874856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jfb6020222
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