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Increasing the Biological Stability Profile of a New Chemical Entity, UPEI-104, and Potential Use as a Neuroprotectant Against Reperfusion-Injury

Previous work in our laboratory demonstrated the utility of synthetic combinations of two naturally occurring, biologically active compounds. In particular, we combined two known anti-oxidant compounds, lipoic acid and apocynin, covalently linked via an ester bond (named UPEI-100). In an animal mode...

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Bibliografiske detaljer
Udgivet i:Brain Sci
Main Authors: Saleh, Tarek M., Connell, Barry J., Kucukkaya, Inan, Abd-El-Aziz, Alaa S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493460/
https://ncbi.nlm.nih.gov/pubmed/25906324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci5020130
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