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Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture

In renal collecting duct (CD) principal cells (PCs), vasopressin (VP) acts through its receptor, V2R, to increase intracellular cAMP leading to phosphorylation and apical membrane accumulation of the water channel aquaporin 2 (AQP2). The trafficking and function of basolaterally located AQP2 is, how...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rice, William L., Li, Wei, Mamuya, Fahmy, McKee, Mary, Păunescu, Teodor G., Lu, Hua A. Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493001/
https://ncbi.nlm.nih.gov/pubmed/26147297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131719
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