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Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture
In renal collecting duct (CD) principal cells (PCs), vasopressin (VP) acts through its receptor, V2R, to increase intracellular cAMP leading to phosphorylation and apical membrane accumulation of the water channel aquaporin 2 (AQP2). The trafficking and function of basolaterally located AQP2 is, how...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4493001/ https://ncbi.nlm.nih.gov/pubmed/26147297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131719 |
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