Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections

Calprotectin, the most abundant cytoplasmic protein in neutrophils, suppresses the growth of Staphylococcus aureus by sequestering the nutrient metal ions Zn and Mn. Here we show that calprotectin can also enhance the activity of the SaeRS two component system (TCS), a signaling system essential for...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Cho, Hoonsik, Jeong, Do-Won, Liu, Qian, Yeo, Won-Sik, Vogl, Thomas, Skaar, Eric P., Chazin, Walter J., Bae, Taeok
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492782/
https://ncbi.nlm.nih.gov/pubmed/26147796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005026
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