Evidence for the Involvement of Potassium Channel Inhibition in the Antidepressant-Like Effects of Hesperidin in the Tail Suspension Test in Mice

The administration of hesperidin elicits an antidepressant-like effect in mice by a mechanism dependent on an interaction with the l-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway, whose stimulation is associated with the activation of potassium (K(+)) channels. Thus, this...

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Published in:J Med Food
Main Authors: Donato, Franciele, Filho, Carlos Borges, Giacomeli, Renata, Alvater, Elza Eliza Tenório, Fabbro, Lucian Del, Antunes, Michele da Silva, de Gomes, Marcelo Gomes, Goes, André Tiago Rossito, Souza, Leandro Cattelan, Boeira, Silvana Peterini, Jesse, Cristiano Ricardo
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492670/
https://ncbi.nlm.nih.gov/pubmed/25647144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jmf.2014.0074
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