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Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy
Significance: The contribution of epigenetic alterations to cancer development and progression is becoming increasingly clear, prompting the development of epigenetic therapies. Histone deacetylase inhibitors (HDIs) represent one of the first classes of such therapy. Two HDIs, Vorinostat and Romidep...
Guardat en:
| Publicat a: | Antioxid Redox Signal |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mary Ann Liebert, Inc.
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492608/ https://ncbi.nlm.nih.gov/pubmed/24730655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.5915 |
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