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Enantioselective β-Protonation by a Cooperative Catalysis Strategy
An enantioselective N-heterocyclic carbene (NHC)-catalyzed β-protonation through the orchestration of three distinct organocatalysts has been developed. This cooperative catalyst system enhances both yield and selectivity, compared to only the NHC-catalyzed process. This new method allows for the ef...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492478/ https://ncbi.nlm.nih.gov/pubmed/25929160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b02887 |
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