Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammation via HMGB1/TLR4 signaling in vitro

AIM: To investigate the inhibitory effects and mechanism of high mobility group box (HMGB)1 A-box in lipopolysaccharide (LPS)-induced intestinal inflammation. METHODS: Overexpression of HMGB1 A-box in human intestinal epithelial cell lines (SW480 cells) was achieved using the plasmid pEGFP-N1. HMGB1...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Wang, Fu-Cai, Pei, Jing-Xuan, Zhu, Jun, Zhou, Nan-Jin, Liu, Dong-Sheng, Xiong, Hui-Fang, Liu, Xiao-Qun, Lin, Dong-Jia, Xie, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491963/
https://ncbi.nlm.nih.gov/pubmed/26167076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i25.7764
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