Diet-induced obesity impairs hypothalamic glucose sensing but not glucose hypothalamic extracellular levels, as measured by microdialysis

BACKGROUND/OBJECTIVES: Glucose from the diet may signal metabolic status to hypothalamic sites controlling energy homeostasis. Disruption of this mechanism may contribute to obesity but its relevance has not been established. The present experiments aimed at evaluating whether obesity induced by chr...

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Publicat a:Nutr Diabetes
Autors principals: de Andrade, I S, Zemdegs, J C S, de Souza, A P, Watanabe, R L H, Telles, M M, Nascimento, C M O, Oyama, L M, Ribeiro, E B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491853/
https://ncbi.nlm.nih.gov/pubmed/26075639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nutd.2015.12
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