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Posterior predictive checks to quantify lack-of-fit in admixture models of latent population structure

Admixture models are a ubiquitous approach to capture latent population structure in genetic samples. Despite the widespread application of admixture models, little thought has been devoted to the quality of the model fit or the accuracy of the estimates of parameters of interest for a particular st...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mimno, David, Blei, David M., Engelhardt, Barbara E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491772/
https://ncbi.nlm.nih.gov/pubmed/26071445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412301112
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