Epidermal TRPM8 channel isoform controls the balance between keratinocyte proliferation and differentiation in a cold-dependent manner

Deviation of the ambient temperature is one of the most ubiquitous stimuli that continuously affect mammals’ skin. Although the role of the warmth receptors in epidermal homeostasis (EH) was elucidated in recent years, the mystery of the keratinocyte mild-cold sensor remains unsolved. Here we report...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bidaux, Gabriel, Borowiec, Anne-sophie, Gordienko, Dmitri, Beck, Benjamin, Shapovalov, George G., Lemonnier, Loïc, Flourakis, Matthieu, Vandenberghe, Matthieu, Slomianny, Christian, Dewailly, Etienne, Delcourt, Philippe, Desruelles, Emilie, Ritaine, Abigaël, Polakowska, Renata, Lesage, Jean, Chami, Mounia, Skryma, Roman, Prevarskaya, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491737/
https://ncbi.nlm.nih.gov/pubmed/26080404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423357112
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