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Testosterone-induced adult neurosphere growth is mediated by sexually-dimorphic aromatase expression

We derived adult neural stem/progenitor cells (NSPCs) from the sub-ventricular zone of male and female mice to examine direct responses to principal sex hormones. In the presence of epidermal growth factor (EGF) and fibroblast growth factor-2 (FGF2) NSPCs of both sexes expressed nestin and sox2, and...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Ransome, Mark I., Boon, Wah Chin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491627/
https://ncbi.nlm.nih.gov/pubmed/26217181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00253
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