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Methotrexate Associated Renal Impairment Is Related to Delayed Elimination of High-Dose Methotrexate
Although Methotrexate (MTX) is an effective drug for the treatment of acute lymphoblastic leukemia (ALL), the toxicity remains a significant problem. In this prospective study, fifty-four patients with ALL were enrolled. 3 g or 5 g MTX/m(2) was administered over 24 hours. Serum MTX concentrations we...
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| Publicado no: | ScientificWorldJournal |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491404/ https://ncbi.nlm.nih.gov/pubmed/26185782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/751703 |
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