Three-Times-Weekly Administration of Teriparatide Improves Vertebral and Peripheral Bone Density, Microarchitecture, and Mechanical Properties Without Accelerating Bone Resorption in Ovariectomized Rats

Daily and weekly administration of teriparatide (PTH(1–34)) reduces the risk of osteoporotic bone fractures. However, their effects on markers of bone formation and bone resorption differ. These results indicate that the dosing frequency of teriparatide may affect bone metabolism and bone structure,...

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Veröffentlicht in:Calcif Tissue Int
Hauptverfasser: Takao-Kawabata, Ryoko, Isogai, Yukihiro, Takakura, Aya, Shimazu, Yukari, Sugimoto, Emika, Nakazono, Osamu, Ikegaki, Ichiro, Kuriyama, Hiroshi, Tanaka, Shinya, Oda, Hiromi, Ishizuya, Toshinori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491365/
https://ncbi.nlm.nih.gov/pubmed/25911187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-015-9998-0
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