Surface display of an anti-DEC-205 single chain Fv fragment in Lactobacillus plantarum increases internalization and plasmid transfer to dendritic cells in vitro and in vivo

BACKGROUND: Lactic acid bacteria (LAB) are promising vehicles for delivery of a variety of medicinal compounds, including antigens and cytokines. It has also been established that LAB are able to deliver cDNA to host cells. To increase the efficiency of LAB-driven DNA delivery we have constructed La...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Christophe, Michon, Kuczkowska, Katarzyna, Langella, Philippe, Eijsink, Vincent G H, Mathiesen, Geir, Chatel, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491208/
https://ncbi.nlm.nih.gov/pubmed/26141059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0290-9
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