Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation

Histidine phosphorylation (pHis) is well studied in bacteria; however, its role in mammalian signaling remains largely unexplored due to the lack of pHis-specific antibodies and the lability of the phosphoramidate (P-N) bond. Both imidazole nitrogens can be phosphorylated, forming 1-phosphohistidine...

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Publicat a:Cell
Autors principals: Fuhs, Stephen Rush, Meisenhelder, Jill, Aslanian, Aaron, Ma, Li, Zagorska, Anna, Stankova, Magda, Binnie, Alan, Al-Obeidi, Fahad, Mauger, Jacques, Lemke, Greg, Yates, John R., Hunter, Tony
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491144/
https://ncbi.nlm.nih.gov/pubmed/26140597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.046
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