Regulatory T Cell DNA Methyltransferase Inhibition Accelerates Resolution of Lung Inflammation

Acute respiratory distress syndrome (ARDS) is a common and often fatal inflammatory lung condition without effective targeted therapies. Regulatory T cells (Tregs) resolve lung inflammation, but mechanisms that enhance Tregs to promote resolution of established damage remain unknown. DNA demethylati...

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Bibliographic Details
Published in:Am J Respir Cell Mol Biol
Main Authors: Singer, Benjamin D., Mock, Jason R., Aggarwal, Neil R., Garibaldi, Brian T., Sidhaye, Venkataramana K., Florez, Marcus A., Chau, Eric, Gibbs, Kevin W., Mandke, Pooja, Tripathi, Ashutosh, Yegnasubramanian, Srinivasan, King, Landon S., D’Alessio, Franco R.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491142/
https://ncbi.nlm.nih.gov/pubmed/25295995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0327OC
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