Dysfunction in gap junction intercellular communication induces aberrant behavior of the inner cell mass and frequent collapses of expanded blastocysts in mouse embryos

PURPOSE: We investigated the role of gap junctions (GJs) in embryological differentiation, and observed the morphological behavior of the inner cell mass (ICM) by time-lapse movie observation (TLM) with gap junction inhibitors (GJis). METHODS: ICR mouse embryos were exposed to two types of GJis in C...

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Detalhes bibliográficos
Publicado no:J Assist Reprod Genet
Main Authors: Togashi, Kazue, Kumagai, Jin, Sato, Emiko, Shirasawa, Hiromitsu, Shimoda, Yuki, Makino, Kenichi, Sato, Wataru, Kumazawa, Yukiyo, Omori, Yasufumi, Terada, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Embryo Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491087/
https://ncbi.nlm.nih.gov/pubmed/25917498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-015-0479-1
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