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Who let the dogs out?: detrimental role of Galectin-3 in hypoperfusion-induced retinal degeneration

BACKGROUND: Retinal ischemia results in a progressive degeneration of neurons and a pathological activation of glial cells, resulting in vision loss. In the brain, progressive damage after ischemic insult has been correlated to neuroinflammatory processes involving microglia. Galectin-3 has been sho...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Manouchehrian, Oscar, Arnér, Karin, Deierborg, Tomas, Taylor, Linnéa
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490716/
https://ncbi.nlm.nih.gov/pubmed/25968897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0312-x
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