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Molecular snapshots of the Pex1/6 AAA+ complex in action

The peroxisomal proteins Pex1 and Pex6 form a heterohexameric type II AAA+ ATPase complex, which fuels essential protein transport across peroxisomal membranes. Mutations in either ATPase in humans can lead to severe peroxisomal disorders and early death. We present an extensive structural and bioch...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Ciniawsky, Susanne, Grimm, Immanuel, Saffian, Delia, Girzalsky, Wolfgang, Erdmann, Ralf, Wendler, Petra
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490564/
https://ncbi.nlm.nih.gov/pubmed/26066397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8331
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