Loading...

A Combined Pharmacophore Modeling, 3D QSAR and Virtual Screening Studies on Imidazopyridines as B-Raf Inhibitors

B-Raf kinase is an important target in treatment of cancers. In order to design and find potent B-Raf inhibitors (BRIs), 3D pharmacophore models were created using the Genetic Algorithm with Linear Assignment of Hypermolecular Alignment of Database (GALAHAD). The best pharmacophore model obtained wh...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Xie, Huiding, Chen, Lijun, Zhang, Jianqiang, Xie, Xiaoguang, Qiu, Kaixiong, Fu, Jijun
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490445/
https://ncbi.nlm.nih.gov/pubmed/26035757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160612307
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!