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Insights into the origin of the nuclear localization signals in conserved ribosomal proteins

Eukaryotic ribosomal proteins, unlike their bacterial homologues, possess nuclear localization signals (NLSs) to enter the cell nucleus during ribosome assembly. Here we provide a comprehensive comparison of bacterial and eukaryotic ribosomes to show that NLSs appear in conserved ribosomal proteins...

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Vydáno v:Nat Commun
Hlavní autoři: Melnikov, Sergey, Ben-Shem, Adam, Yusupova, Gulnara, Yusupov, Marat
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490412/
https://ncbi.nlm.nih.gov/pubmed/26066547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8382
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