TCF12 is mutated in anaplastic oligodendroglioma

Anaplastic oligodendroglioma (AO) are rare primary brain tumours that are generally incurable, with heterogeneous prognosis and few treatment targets identified. Most oligodendrogliomas have chromosomes 1p/19q co-deletion and an IDH mutation. Here we analysed 51 AO by whole-exome sequencing, identif...

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Pubblicato in:Nat Commun
Autori principali: Labreche, Karim, Simeonova, Iva, Kamoun, Aurélie, Gleize, Vincent, Chubb, Daniel, Letouzé, Eric, Riazalhosseini, Yasser, Dobbins, Sara E., Elarouci, Nabila, Ducray, Francois, de Reyniès, Aurélien, Zelenika, Diana, Wardell, Christopher P., Frampton, Mathew, Saulnier, Olivier, Pastinen, Tomi, Hallout, Sabrina, Figarella-Branger, Dominique, Dehais, Caroline, Idbaih, Ahmed, Mokhtari, Karima, Delattre, Jean-Yves, Huillard, Emmanuelle, Mark Lathrop, G., Sanson, Marc, Houlston, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490400/
https://ncbi.nlm.nih.gov/pubmed/26068201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8207
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