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Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na(+) retention

Pregnancy is characterized by plasma volume expansion due to Na(+) retention, driven by aldosterone. The aldosterone-responsive epithelial Na(+) channel is activated in the kidney in pregnancy. In the present study, we investigated the aldosterone-responsive Na(+)-Cl(−) cotransporter (NCC) in mid- a...

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Publicado en:Am J Physiol Renal Physiol
Autores principales: West, Crystal A., McDonough, Alicia A., Masilamani, Shyama M. E., Verlander, Jill W., Baylis, Chris
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490381/
https://ncbi.nlm.nih.gov/pubmed/25925254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00147.2015
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