Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates

The development of an efficacious Plasmodium falciparum malaria vaccine remains a top priority for global health. Vaccination with irradiated sporozoites is able to provide complete sterile protection through the action of CD8(+) T cells at the liver-stage of infection. However, this method is curre...

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Vydáno v:Sci Rep
Hlavní autoři: Longley, Rhea J., Salman, Ahmed M., Cottingham, Matthew G., Ewer, Katie, Janse, Chris J., Khan, Shahid M., Spencer, Alexandra J., Hill, Adrian V. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490344/
https://ncbi.nlm.nih.gov/pubmed/26139288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11820
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