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Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2

Na(+)/H(+) exchange by Na(+)/H(+) exchanger 3 (NHE3) is a major route of sodium absorption in the intestine and kidney. We have shown previously that lysophosphatidic acid (LPA), a small phospholipid produced ubiquitously by all types of cells, stimulates NHE3 via LPA(5) receptor. Stimulation of NHE...

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Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: No, Yi Ran, He, Peijian, Yoo, Byong Kwon, Yun, C. Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490325/
https://ncbi.nlm.nih.gov/pubmed/25855080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00067.2015
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